Novel Drug Delivery Systems
Drug delivery is the process of administering the drug or pharmaceutical product, in order to achieve desired therapeutic effect. The method by which drug delivered is important, as it has significant effect on its efficacy. Novel drug delivery system involves various approaches like medical devices or drug-device combination products. Novel drug delivery system (NDDS) involves combining polymer science, pharmaceutics and molecular biology. Novel drug delivery systemsare designed based on physical and biochemical mechanisms. Physical mechanism or controlled drug delivery system includes dissolution, osmosis, erosion and diffusion. Biochemical mechanism includes gene therapy, liposomes, nanoparticles, monoclonal antibodies. NDDS drugs are designed to target the site specific region, in order to achieve desired therapeutic effect, thereby reducing the side or toxic effects. Various drug delivery and drug targeted systems are developed, in order to minimize drug degradation, drug adverse effect, and in order to increase the drug bioavailability(amount of drug available at site targeted region). Site specific drug delivery may be either active or passive process.
- Micelles
- Liposomes
- Dendrimers
- Nano particles
- Hydrogels
- Fast dissolving tablets (fdt)
- Iontophoresis
- Phonophoresis
- Erythrocytes
- Microspheres
- Magnetic microparticles